JMS-S3000 SpiralTOF™ series Life Science Applications Notebook

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Edition June 2020

JMS-S3000 SpiralTOF(TM) series Life Science Applications Notebook

This is a compendium of life science related applications notes, JEOL News articles, and scientific journal articles based on the data acquired on JEOL ultra-high mass-resolution MALDI-TOFMS JMS-S3000 SpiralTOF™ series.

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Table of Contents

Introduction and Fundamentals P1~

  • Development of JMS-S3000: MALDI-TOF/TOF Utilizing a Spiral Ion Trajectory
    (Takaya Satoh, JEOL News, 45, 34-37, 2010)
  • The Relationship between Crystal Condition and Mass Resolving Power, Mass Accuracy (MSTips No.206)

Proteins and Peptides P11~

  • High-Resolution Measurements of Proteins Using the Spiral Mode of JMS-S3000 "SpiralTOF™" (MSTips No.297)
  • MALDI-ISD Measurements Using Both the SpiralTOF™ Mode and the Linear Mode (MSTips No.229)
  • High Resolution and High Mass Accuracy MALDI-ISD Measurements (MSTips No.228) 
  • High Sensitivity Analysis of Intact Proteins Using Linear TOF (MSTips No.227) 
  • High Sensitivity Peptide Measurement with the New Matrix α-Cyano-4-Chlorocinnamic Acid
  • Distinguishing Lysine and Glutamine in a Peptide
  • Analysis of Phosphopeptide Using TOF-TOF (MS Tips No.184) 
  • Comparison of the JMS-S3000 SpiralTOF™-TOF and a 4-Sector Tandem Double-Focusing Mass Spectrometer (MS Tips No.181)
  • Structural Analysis of a High Molecular Weight Peptide (MS Tips No.175)
  • High-Energy CID Analysis of Bovine Serum Albumin (MS Tips No.174)
  • Analysis of Bovine Serum Albumin (MS Tips No.166)

Lipids P39~

  • Structural Analysis of Triacylglycerols by Using a MALDI-TOF/TOF System with Monoisotopic Precursor Selection
    (Kubo, A., et al., J. Am. Soc. Mass Spectrom., 24, 684-689, 2013; open access article © The Authors, 2012)
  • Structural Analysis of Oxidized Triolein (MS Tips No.197) 
  • Structural Analysis of Triolein (MS Tips No.182)
  • Structural Analysis of Tristearin (MS Tips No.178)

Natural Products / Oligosaccharides P51~

  • Analysis of the Natural Organic Compound SAAF by Using the TOF-TOF Option (MS Tips No.183)
  • Analysis of the Natural Organic Compound YTX by Using the TOF-TOF Option
  • High-energy CID Mass Spectrometry of Oligosaccharides

Drugs / Small Molecules P59~

  • Structural analysis of melatonin and related compounds using JMS-S3000 SpiralTOF™ with the TOF-TOF option (MSTips No.256) 
  • Analysis of medicinal properties in a combination cold remedy by using JMS-S3000 "SpiralTOF™" (MSTips No.241)
  • High-Energy CID MS-MS Analysis of Small Organic Molecules (MS Tips No.173)
  • MALDI for Small Molecule Analysis: A Complex Drug Mixture
  • Accurate mass measurement of small organic molecules using JMS-S3000 "SpiralTOF™" (MS Tips No.168) 

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