Realization of an Innovative Metrological Traceability Using the Quantitative NMR Method

  • Summary

JEOLnews Volume 47, Number 1, 2012 Toshihide Ihara and Takeshi Saito
National Metrology Institute of Japan, National Institute of Advanced Industrial Science and Technology

Reference materials are indispensable for accurate analysis of hazardous substances in food and environment. For organic substances, however, the dissemination of reference materials is hopelessly unable to catch up with today’s rapidly proliferating analytical needs. To solve this problem, analytical techniques were improved to develop a method in which a single primary reference material could provide accurate quantitative measurements for a wide variety of organic compounds. In this approach, we turned our attention to the 1H NMR method. We improved the method to perform precise comparisons of signal quantities from protons at different chemical shifts, enabling quantitative analysis at an acceptable level of uncertainty for a variety of organic reference materials by using a primary reference material for protons. Based on this achievement, an innovative metrological traceability capable of minimizing the number of national reference materials was realized, thus enabling us to have a prospect for rapid expansion of reference materials used in food and environmental analyses.
Please see the PDF file for the additional information.
Click on the image, you will be redirected to the JEOL members site and the PDF file will be downloaded.

※For viewing the latest version of JEOL news, registration is required.

PDF 277KB

Related Products