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Features

JNM-ECZL series FT NMR

The ECZ Luminous (JNM-ECZL series) is an FT NMR spectrometer equipped with state-of-the-art digital and high frequency technology. The highly integrated Smart Transceiver System, a high-speed, high-precision digital high-frequency control circuit, enables further miniaturization and high reliability of the spectrometer. It is capable of high-field and solid-state NMR measurements while maintaining the size of a conventional low-field solution NMR system.

The new Multi Frequency Drive System enables multi-resonance measurements in a standard configuration, providing a wider range of solutions. We hope you enjoy the world of ECZ Luminous.

STS (Smart Tranceiver System)

The ECZ Luminous inherits the STS (Smart Transceiver System) digital high integration and high frequency technology used in the previous ECZ series. The sequencer, DDS (Direct Digital Synthesizer), FSU (Frequency Synthesizer Unit), transmitter, receiver, acquisition unit, and gate control unit are all integrated on a single RF (Radio Frequency) transmitter/receiver board. Two 4-frequency source units (one each for HF and LF) and one receiver are configured on a single RF transmitter/receiver board. The standard configuration has a total of eight frequency sources and one receiver. The ECZ Luminous can be expanded to four RF transmitter/receiver boards to support up to 8 nuclei, 32-frequency sources and four receivers. In addition, the transmitter/receiver system in the STS is a hybrid of direct conversion oversampling and superheterodyne undersampling technologies, which allows for flexible frequency conversion and efficient and optimal signal transmission/reception depending on the target frequency.

Frequency modulation changed from 0 to 10 MHz.

Highly Precise Digital Control

The ECZ Luminous sequencer provides fast control of frequency, phase and amplitude modulation with a minimum control time resolution of 5 ns. In addition, the ECZ Luminous is equipped with a digital quadrature detection (DQD) circuit that enables dynamic frequency and phase modulation synchronously or asynchronously in both the transmitter and receiver systems. This enables signal processing with high functionality and a high degree of freedom, and is expected to be applied to cutting-edge solid- state NMR measurements, which have become increasingly important in recent years. In addition, a unique streaming transfer technology is used for the sequence memory, which has a quasi-infinite memory capacity. At the same time, the same control performance is provided for various gating and synchronization operations with external systems. These high-speed, high-accuracy digital control technologies provide the best solution for a wide variety of requirements to realize a wide range of advanced NMR measurements. In case that observe nucleus has a wide range of chemical shifts, such as 19F, some signals may not be observed due to the limited bandwidth of conventional rectangular pulses. In such a case, high-speed phase modulation pulses excite much wider ranges and are very useful.

PM-BEBOP180 Phase modulated pulse
PM-BEBOP180 Phase modulated pulse
1H decoupled 19F-13C HMQC 2D spectrum
1H decoupled 19F-13C HMQC 2D spectra

Wide Dynamic Range

The receivers in the ECZ Luminous are sequencer controlled and can be independently and dynamically frequency and phase modulated for sampling. DQD (Digital Quadrature Detection) with 16-bit 100Msps high-speed A/D conversion not only improves the effective dynamic range against quantization noise by high rate oversampling, but also reduces unwanted signals such as intermodulation distortions (IMDs) to the utmost limit. The digital filter is optimized for NMR and ensures quantitative performance over a wide bandwidth.
The high dynamic range of ECZ Luminous allows you to clearly capture small signals in NMR spectra, including large signals such as solvent.

A small 13C satellite signal (about 4.6 millionths) of the acetone signal in a 	mixed sample: H2O:DMSO:Acetone=25131:125:1 (about 10 % D2O) is 	clearly visible.
A small 13C satellite signal (about 4.6 millionths) of the acetone signal in a mixed sample: H2O:DMSO:Acetone=25131:125:1 (about 10 % D2O) is clearly visible.

Low-noise Wideband SiGe Preamplifier

Newly developed low-noise wideband SiGe preamplifier improves sensitivity. In combination with ROYALPROBE™ / ROYALPROBE™ HFX, the sensitivity has been improved by about 10 %.

Digital Lock Circuit for Stability

The ECZ Luminous uses STS technology to digitally control the 2H lock with high speed and high accuracy. The excellent response control of the digital feedback circuit suppresses the effects of magnetic field fluctuations more efficiently. The high speed and high precision digital lock feedback function enables stable and long time measurement.

Stability test data over 12 hours
Stability test data over 12 hours
1D 1H-13C HMQC needs to observe the correlated signal (left and right signals) of 13C-coupled 1H, which has an existence ratio of about 1 %, and eliminate the directly observed signal of 12C-coupled 1H, which has an existence ratio of about 99 %. This is why it is used to check stability.

MFDS (Multi Frequency Drive System)

We have developed a new Multi Frequency Drive System. Expanding on the design concept of the HFX system, the ECZ Luminous system enables multiple resonance measurements using triple-resonance probes such as HCN and HCX probes on a standard two-channel spectrometer. Conventional triple-resonance measurements, which require pulse irradiation of three or more nuclides with different frequencies, traditionally require costly expansion of channels and installation space. With ECZ Luminous, the multi-sequencer architecture with STS and the newly-developed MFDS (Multi Frequency Drive System) enable triple-resonance measurements with a two-channel spectrometer. It opens the door of multiple-resonance experiments to more users.

5 mm HCN probe configuration with ECZ Luminous System

HCN probe configuration with ECZ Luminous System
HCP triple resonance experiment performed by 2 channel spectrometer
HCP triple resonance experiment performed by 2 channel spectrometer
(13C-31P {1H} correlation)
HCN triple resonance experiment performed by 2 channel spectrometer
HCN triple resonance experiment performed by 2 channel spectrometer
(CBCACONH)

Easy Shimming

The ECZ Luminous includes a digital matrix shim system (25 shims) for 400 MHz, and a Lagrange shim system (44 shims) for higher-field instruments requiring higher resolution.

Gradient shimming is a technique that uses a magnetic field gradients to measure the magnetic field distribution in the sample space, and then immediately calculate and apply the appropriate shim values. Gradient shimming allows rapid and automatic optimization of the shims, even for samples with small volumes or different solvent systems, to obtain NMR spectra with the highest resolution.

ECZ Luminous can perform gradient shimming by observing nuclei other than 2H (D) and 1H nuclei. For example, if you want to perform NMR measurements on a sample that is only soluble in fluorinated solvents, you can adjust the resolution by gradient shimming on 19F. The accelerated 3D gradient shimming (3 axes) measures the 3D magnetic field map of the sample and calculates and applies the optimal shim value for the radial terms, making it easy to optimize resolution in various conditions.

Gradient shimming (2H)
Gradient shimming 2H
Spectra before and after resolution adjustment by gradient shim. The resolution is improved by 20 seconds
Gradient shimming (19F)
Gradient shimming 19F
You can select the 19F signal and use it to adjust the resolution with gradient shimming as well as the 2H signal.
Poorly adjusted radial shims under sample rotation (top) and corrected with 3D gradient shimming (bottom)
Poorly adjusted radial shims under sample rotation (top) and corrected with 3D gradient shimming (bottom)

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Specifications

More compact spectrometer

ECZ Luminous has achieved a significant reduction in size while enhancing the performance of the spectrometer. The volume of the R series has been reduced to about 1/3 of that of the conventional equivalent.

Size comparison with conventional models with equivalent performance
Size comparison with conventional models with equivalent performance
JNM-ECZL G series JNM-ECZL R series JNM-ECZL S series
Frequency 400 MHz - 1.3 GHz 400 MHz - 600 MHz 400 MHz
Sample type Solution / Solid Solution / Solid Solution
Number of channels 2 (standard) 2 2
Power amplifier 100 W (standard) 100 W 50 W
 High frequency 200/500/1000 W (as option)
Power amplifier 300 W (standard) 300 W 150 W
 Low frequency 500/1000/2000 W (as optiona)
Magnetic field gradient amplifier 10 A (standard) 10 A 10 A
30/50 A (as option)
Console size W×D×H 600×855×1,279 mm 536×730×855 mm 536×730×855 mm

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