• Features
  • Application
  • Related Products
  • Information

Features

ROYALPROBE HFX
The ROYALPROBE HFX is the world’s first liquid NMR probe switchable between single tune and dual tune mode on the High Frequency coil without compromising the NMR performance. The ROYALPROBE HFX operating in single tune mode has the performance for sensitivity and pulse width as the standard ROYALPROBE. Operating the ROYALPROBE HFX in dual tune mode allows for a wide variety 1H and 19F of advanced NMR experiments including 1H{19F}, 19F{1H}, 13C{1H,19F}, and many unique 13C{1H, 19F} correlation experiments to simplify spectral assignments of modern complex fluorine containing compounds for the pharmaceutical and polymer industries. The Low Frequency coil is not limited to 13C, but can be tuned to any nucleus between 31P and 15N with the same experimental flexibility as 13C experiments a feature unique to the ROYALPROBE HFX.
The JEOL ROYALPROBE HFX is the world’s first liquid NMR probe switchable between single tune and dual tune mode on the High Frequency coil without compromising the NMR performance.* The ROYALPROBE HFX operating in single tune mode has the same sensitivity and pulse width performance as the standard ROYALPROBE.
*As of February, 2017
Two probes merged into one
The JEOL ROYALPROBE HFX

Application examples of ROYALPROBE HFX -1-

Operating the ROYALPROBE HFX in dual tune mode allows for a wide variety 1H and 19F of advanced NMR experiments including 1H{19F}, 19F{1H},13C{1H,19F}, and many unique 13C{1H, 19F} correlation experiments to simplify spectral assignments of modern complex fluorine containing compounds for the pharmaceutical and polymer industries.
19F -NMR examples measured on a standard two RF channel JNM-ECZ500R

25mg, 1,1,2,3,3,3-Hexafluoropropyl ethyl ether / CDCl3 13C-NMR 256scans

Application examples of ROYALPROBE HFX -2-

2D 1H-13C HSQC with 19F decoupling, collected on a JEOL JNM-ECZ500R with optional HF2 19F 3rd channel

CRISIS-HSQCAD, 25% NUS 4scans

1H-13C gHMBCAD, 19F Decoupling Simplifies Assignments, 25% NUS, 8 Scans
10mg Fluticasone Propionate / DMSO-d6
 

Application examples of ROYALPROBE HFX -3-

The Low Frequency coil is not limited to 13C, but can be tuned to any nucleus between 31P and 15N with the same experimental flexibility as 13C experiments a feature unique to the ROYALPROBE HFX. 

10mg, Decafluorotriphenyl Phosphine / CDCl3
collected on a JEOL JNM-ECZ500R with optional HF2 19F 3rd channel


25mg 2,3-difluoro-5-(trifluoromethyl)pyridine /Benzene-d6 1H-15N HMBC 4scans

Link

Specifications

Gallery

Related Products

Information

Installation Examples