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An ultra high sensitivity 5mm tuneable probe using cryogenic technologies. Dramatic noise reduction is achieved by cryo-cooling of both the detection coil and the preamplifier which yields 4-5x higher sensitivity than conventional probes. Thus, a measurement that took a day and night, may now be complete in a lunch break. This probe is compatible with the Autotune control unit thus consecutive measurements can include change of nucleus as well as different experiments.