NMR Challenge – Moving into the future with an evolution of reliability

Quantitative NMR

Quantitative analysis is essential to our daily lives, supporting activities like health checks, content labeling for foods and pharmaceutical products, and the monitoring of harmful substances. Quantitative NMR (qNMR) has recently been a focus of attention as an even more reliable method of performing quantitative analysis.
To enhance the reliability of quantitative analysis and contribute to the safety and security of society, JEOL is involved in the development of equipment and software, and offers comprehensive support, in addition to contributing to the (international) standardization of qNMR methodologies.

What is qNMR ?

Quantitative NMR or qNMR is quantitative analysis using NMR.
The principle difference from other quantitative analytical methods is absolute quantitative analysis method which does not require the same standard substance as an analyte.

Quick Introduction to Quantitative NMR

No. Title
Issue 1 Welcome! Quick Introduction to Quantitative NMR
Issue 2 Chromatographic methods of quantification and NMR quantification
Issue 3 The reason quantitative analysis is possible with NMR
Issue 4 Using Quantitative NMR
Issue 5 Keyword for Reliability of Analysis Results: Traceability
Issue 6 Is Quantitative NMR Changing Quantitative Analysis (1)?
Issue 7 Is Quantitative NMR Changing Quantitative Analysis (2)?
Issue 8 Let’s try doing quantitative NMR
Issue 9 Let’s try doing quantitative NMR (2)

Topics

News

Relevant sites

  • Standards for qNMR: Wako Pure Chemical Industries, Ltd.
  • NMR validation
  • ISRD (qNMR Internal Standard Reference Data):BIPM 
    https://www.bipm.org/en/bipm/chemistry/organic-analysis/qnmr/

    BIPM (International Bureau of Metrology) is conducting research on analytical methods of standard substances using qNMR. ISRD of maleic acid has been released as information on reference standard for qNMR.
    Evaluation of physical properties for use as a reference standard for qNMR is gathered and it is information necessary for selection of reference standard. This information is scheduled to be released on BIPM's HP, and it will be useful for selection of reference standard to implement qNMR.

Events

  • Date/Period: Nov. 24, 2017
    Location: Aula Magna A. Alto, Bari, Italy
  • Date/Period: Jan. 29 - 30, 2018
    The 2018 qNMR Summit will be held on the 29th and 30th of January, 2018, in Tokyo, Japan.
    This Summit is being hosted by JEOL Ltd, Wako Pure Chemical Industries Ltd. and is being implemented under the auspices of the Japanese Ministry of Economy, Trade, and Industry 2017 “Initiative to Promote Strategic International Standardization”.
    This initiative is an international standardization development activity related to strategic fields of governmental development”.
  • Date/Period: Oct. 10 - 11, 2018
    Location: University of Würzburg (Germany)

Products

Application note

Reference information

Introduction Example